Department of Cardiology, Infanta Sofia Hospital, San Sebastián de los Reyes, Madrid, Spain.
J Clin Hypertens (Greenwich). 2010 May;12(5):374-9. doi: 10.1111/j.1751-7176.2009.00259.x.
This study was performed to determine the effectiveness of a cardiac rehabilitation and exercise training program on metabolic parameters and coronary risk factors in patients with the metabolic syndrome and coronary heart disease. The study involved 642 patients with coronary heart disease. Of them, 171 (26.7%) fulfilled criteria for the metabolic syndrome. Clinical data, laboratory tests, and exercise testing were performed before and after the program, which lasted 2 to 3 months. Except for waist circumference, there were no significant differences between groups; blood pressure, high-density lipoprotein cholesterol, triglycerides, and fasting glucose improvements during the follow-up were higher in patients with the metabolic syndrome (all P<.001). At study end, in patients with the metabolic syndrome, functional capacity increased by 26.45% ( P<.001), as measured by metabolic equivalents, with a slight increase of 1.25% ( P=not significant) in the double product. Patients with the metabolic syndrome who took part in this secondary prevention program reported improvements in cardiovascular risk profile and functional capacity.
本研究旨在确定心脏康复和运动训练计划对代谢综合征和冠心病患者代谢参数和冠心病危险因素的有效性。该研究纳入了 642 例冠心病患者。其中,171 例(26.7%)符合代谢综合征标准。在计划开始前和结束后,进行了临床数据、实验室检查和运动测试,该计划持续 2 至 3 个月。除腰围外,两组间无显著差异;代谢综合征患者在随访期间血压、高密度脂蛋白胆固醇、甘油三酯和空腹血糖改善更显著(均 P<.001)。研究结束时,代谢综合征患者的运动能力通过代谢当量增加了 26.45%(P<.001),双乘积仅略有增加 1.25%(P=无显著差异)。参加这个二级预防计划的代谢综合征患者报告说他们的心血管风险状况和功能能力有所改善。