培养板表面特定区域中分化的神经元来自于小鼠胚胎干细胞的积累。

Accumulation of neurons differentiated from mouse embryonic stem cells in particular areas of culture plate surface.

机构信息

Bio-Nano Electronics Research Center, Toyo University, 2100 Kujirai, Kawagoe-shi, Saitama 350-8585, Japan.

出版信息

J Biosci Bioeng. 2010 Aug;110(2):238-41. doi: 10.1016/j.jbiosc.2010.01.012. Epub 2010 Feb 6.

DOI:10.1016/j.jbiosc.2010.01.012

PMID:20547340

Abstract

Nanoscale magnetic beads coated with nerve growth factor (NGF) allow us to accumulate neurons differentiated from mouse ES cells in a selected area of the culture plate surface using a magnet. Neurons with neurite outgrowths within a particular area expressed TrkA and incorporated beads in the soma.

摘要

经纳米磁珠包被的神经生长因子（NGF）使我们能够利用磁场在培养板表面的特定区域内富集由小鼠胚胎干细胞分化而来的神经元。在特定区域内具有突起生长的神经元表达 TrkA 并将磁珠纳入胞体。