耐甲氧西林金黄色葡萄球菌携带的成功治疗及随访的重要性。
Successful treatment for carriage of methicillin-resistant Staphylococcus aureus and importance of follow-up.
机构信息
Erasmus University Medical Center Rotterdam, Department of Medical Microbiology & Infectious Diseases, Postbus 2040, 3000 CA Rotterdam, The Netherlands.
出版信息
Antimicrob Agents Chemother. 2010 Sep;54(9):4020-5. doi: 10.1128/AAC.01240-09. Epub 2010 Jun 14.
Abstract
With this prospective observational follow-up study of 165 methicillin-resistant Staphylococcus aureus (MRSA)-positive individuals (23 health care workers and 142 patients), we determined that our MRSA eradication therapy protocol results in a high success rate (81%). Five or more negative culture sets give a predictive value for MRSA eradication therapy success of >90%. Furthermore, MRSA colonization, at least in the throat, and the presence of wounds just before the start of MRSA eradication therapy are associated with MRSA eradication therapy failure.
摘要
本前瞻性观察随访研究纳入了 165 例耐甲氧西林金黄色葡萄球菌（MRSA）阳性个体（23 名医护人员和 142 名患者），结果显示我们的 MRSA 根除治疗方案成功率高（81%）。5 次或以上的阴性培养结果对 MRSA 根除治疗的成功率有 >90%的预测价值。此外，MRSA 定植（至少在咽喉部）和在开始 MRSA 根除治疗前存在伤口与 MRSA 根除治疗失败相关。
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