Department of Psychology, Oakland University, Rochester, MI 48309, USA.
Int J Obes (Lond). 2011 Jan;35(1):134-41. doi: 10.1038/ijo.2010.120. Epub 2010 Jun 15.
The expanding overweight and obesity epidemic notwithstanding, little is known about their long-term effect on health-related quality of life (HRQoL). The main objective of this study was to investigate whether overweight (body mass index (BMI) 25 to <30 kg m(-2)) and obese (BMI ≥ 30 kg m(-2)) young adults have poorer HRQoL 20 years later.
We studied 3014 participants in the Coronary Artery Risk Development in Young Adults (CARDIA) study, a longitudinal, community-dwelling, biracial cohort from four cities. BMI was measured at baseline and 20 years later. HRQoL was assessed by the Physical Component Summary (PCS) and the Mental Component Summary (MCS) scores of the Medical Outcomes Study 12-Item Short-Form Health Survey at year 20. Higher PCS or MCS scores indicate better HRQoL.
Mean year 20 PCS score was 52.2 for normal weight participants at baseline, 50.3 for overweight and 46.4 for obese (P-trend <0.001). This relation persisted after adjustment for baseline demographics, general health, and physical and behavioral risk factors and after further adjustment for 20-year changes in risk factors. No association was observed for MCS scores (P-trend 0.43).
Overweight and obesity in early adulthood are adversely associated with self-reported physical HRQoL, but not mental HRQoL 20 years later.
尽管超重和肥胖的流行不断扩大，但人们对其对健康相关生活质量（HRQoL）的长期影响知之甚少。本研究的主要目的是调查超重（BMI 25 至 <30kg/m²）和肥胖（BMI ≥ 30kg/m²）的年轻成年人 20 年后的 HRQoL 是否更差。
我们研究了来自四个城市的冠状动脉风险发展在年轻人（CARDIA）研究中的 3014 名参与者，这是一项纵向、社区居住、双种族队列研究。在基线和 20 年后测量 BMI。HRQoL 通过医疗结果研究 12 项简短健康调查的身体成分摘要（PCS）和心理成分摘要（MCS）评分来评估。较高的 PCS 或 MCS 分数表示更好的 HRQoL。
基线时正常体重参与者的平均 20 年 PCS 评分为 52.2，超重者为 50.3，肥胖者为 46.4（P 趋势 <0.001）。在调整基线人口统计学、一般健康以及身体和行为风险因素后，这种关系仍然存在，并且在进一步调整 20 年风险因素变化后仍然存在。MCS 评分无相关性（P 趋势 0.43）。
成年早期超重和肥胖与自我报告的身体 HRQoL 呈负相关，但与 20 年后的心理 HRQoL 无关。
