结节性硬化症患者的超声心动图筛查结果
Echocardiographic screening results in patients with tuberous sclerosis complex.
作者信息
Adriaensen Miraude E A P M, Cramer Maarten J M, Brouha Madelon E E, Schaefer-Prokop Cornelia M, Prokop Mathias, Doevendans Pieter A F M, Zonnenberg Bernard A, Feringa Harm H H
机构信息
Department of Radiology, Atrium Medical Center, 6419 PC Heerlen, The Netherlands.
出版信息
Tex Heart Inst J. 2010;37(3):280-3.
We sought to examine the frequency of abnormal echocardiographic findings in patients with tuberous sclerosis complex. In a retrospective cohort study, we included all patients with known tuberous sclerosis complex who had been sent to our cardiology department for echocardiographic screening from 1995 through August 2003 (n=56). Two research scientists independently reviewed the reports of the echocardiographic screening examinations for abnormal findings. We used descriptive statistics, the Mann-Whitney U test, and the chi(2) test. The mean age of patients included in the study was 35 years (range, 12-73 yr); 23 patients were male. Abnormal findings were seen in 22 patients (39%). The most common abnormal findings were focal areas of increased intramyocardial echogenicity, which were seen in 16 patients (29%). The clinical consequence of this finding is still unknown. We conclude that echocardiographic abnormalities are common in patients with tuberous sclerosis complex.
我们试图研究结节性硬化症患者超声心动图异常表现的频率。在一项回顾性队列研究中，我们纳入了1995年至2003年8月期间因超声心动图筛查而被送至我们心脏病科的所有已知结节性硬化症患者（n = 56）。两名研究科学家独立审查超声心动图筛查检查报告以寻找异常表现。我们使用了描述性统计、曼-惠特尼U检验和卡方检验。纳入研究的患者平均年龄为35岁（范围12 - 73岁）；23例为男性。22例患者（39%）有异常表现。最常见的异常表现是心肌内回声增强的局灶性区域，见于16例患者（29%）。这一表现的临床后果仍不清楚。我们得出结论，结节性硬化症患者中超声心动图异常很常见。
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