Go Jae Wan, Oh Hwa Eun, Cho Han Kyoung, Kang Won Hyoung, Ro Byung In
Department of Dermatology, Myongji Hospital, Kwandong University College of Medicine, Goyang, Korea.
Ann Dermatol. 2010 May;22(2):229-31. doi: 10.5021/ad.2010.22.2.229. Epub 2010 May 18.
Basaloid follicular hamartoma (BFH), uncommon rare benign neoplasm connected to the adnexal structures, presents with multiple clinical manifestations that can develop into basal cell carcinoma. BFH may be congenital or acquired, and the congenital form can be further divided into the generalized and unilateral type, and the acquired form may present as localized and solitary lesions. Congenital, generalized BFH is associated with systemic diseases such as alopecia, cystic fibrosis, hypohidrosis, and myasthenia gravis. In contrast, sporadic cases are observed as unilateral or localized lesions. BFH shows thick cords and thin strands of anastomosing basaloid proliferations that arise from hair follicles and are enclosed by loose fibrous stroma. Here, we report a 70-year-old man with an acquired, solitary form of BFH.
基底样毛囊错构瘤（BFH）是一种与附属器结构相关的罕见良性肿瘤，具有多种临床表现，可发展为基底细胞癌。BFH 可能是先天性的或后天获得性的，先天性形式可进一步分为全身性和单侧型，后天获得性形式可能表现为局限性和孤立性病变。先天性全身性 BFH 与脱发、囊性纤维化、少汗症和重症肌无力等全身性疾病有关。相比之下，散发性病例表现为单侧或局限性病变。BFH 表现为从毛囊产生的相互吻合的基底样增生的粗条索和细束状结构，并被疏松的纤维间质包绕。在此，我们报告一名 70 岁患有后天获得性孤立型 BFH 的男性患者。
