Kim Kyu Ri, Lee Ji Yeoun, Kim Mi Kyeong, Yoon Tae Young
Department of Dermatology, School of Medicine and the Medical Research Institute, Chungbuk National University, Cheongju, Korea.
Ann Dermatol. 2010 May;22(2):232-4. doi: 10.5021/ad.2010.22.2.232. Epub 2010 May 18.
Erosive pustular dermatosis of the scalp (EPDS) is a rare disorder of the elderly characterized by multiple pustular lesions with erosions and crusting that result in scarring alopecia. EPDS typically develops in aged or sun-damaged skin with a history of trauma. Histopathologically, EPDS is nonspecific, showing atrophic epidermis and chronic inflammation. Bacteriological and mycological investigations of EPDS are generally negative. Although herpes zoster is a common disorder in elderly people, previously reported cases of EPDS were rarely associated with herpes zoster. We present a rare case of EPDS following herpes zoster treated successfully with topical tacrolimus.
头皮糜烂性脓疱病(EPDS)是一种老年人的罕见疾病,其特征为多个脓疱性损害伴糜烂和结痂,可导致瘢痕性脱发。EPDS通常发生于有创伤史的老年或受阳光损伤的皮肤。组织病理学上,EPDS无特异性,表现为表皮萎缩和慢性炎症。EPDS的细菌学和真菌学检查通常为阴性。虽然带状疱疹在老年人中是一种常见疾病,但先前报道的EPDS病例很少与带状疱疹相关。我们报告1例带状疱疹后发生EPDS的罕见病例,经外用他克莫司成功治疗。