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[中药滋补剂对患淋巴白血病小鼠细胞膜流动性的影响]

[Effect of herbal tonic on the membrane fluidity of the mice suffered from lymphatic leukemia].

作者信息

Chen Z T, Gu Z D

机构信息

Affiliated Hospital of Shandong College of TCM, Jinan.

出版信息

Zhong Xi Yi Jie He Za Zhi. 1991 Jan;11(1):39-40, 6.

PMID:2054893
Abstract

UNLABELLED

By using fluorescence polarization technology, the authors have studied variations in the membrane fluidity of red blood cell and spleen lymphocytes of the mice with lymphatic leukemia (L7212) untreated or treated by the compound tonic of traditional Chinese medicine decoction of reinforcing Qi and nourishing Yin and decoction of reinforcing Qi and nourishing blood. It was not only confirmed that the membrane fluidity of malignant lymphocytes increased more greatly, but also discovered that the variations could appear in early period of leukemia. The membrane fluidity of lymphocytes of the mice with leukemia treated by the herbal tonic could drop to normal level. But the membrane fluidity of the red blood cell between the normal mice (615) and the leukemia mice (L7212), untreated or treated by the herbal tonic, had no significant difference.

RESULT

the above mentioned suggests the herbal tonic could resist leukemia by reducing the membrane fluidity of the lymphocytes and improving structure and function of the membrane.

摘要

未标记

作者运用荧光偏振技术,研究了未经治疗以及经益气养阴中药复方汤剂和气血双补中药复方汤剂治疗的淋巴白血病(L7212)小鼠红细胞和脾淋巴细胞的膜流动性变化。不仅证实恶性淋巴细胞的膜流动性增加更为显著,还发现这些变化可在白血病早期出现。经中药滋补剂治疗的白血病小鼠淋巴细胞的膜流动性可降至正常水平。但正常小鼠(615)与未经治疗或经中药滋补剂治疗的白血病小鼠(L7212)的红细胞膜流动性无显著差异。

结果

上述情况表明中药滋补剂可通过降低淋巴细胞的膜流动性以及改善膜的结构和功能来抵抗白血病。

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