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青少年鼻咽血管纤维瘤患者的七年经验。

A seven-year experience with patients with juvenile nasopharyngeal angiofibroma.

出版信息

Braz J Otorhinolaryngol. 2010 Mar-Apr;76(2):245-50. doi: 10.1590/S1808-86942010000200016.

Abstract

UNLABELLED

Juvenile nasopharyngeal angiofibroma (JNA) is a rare tumor in adolescent males. It originates in the nasopharynx.

AIM

To present the experience of JNA management at an Otorhinolaryngology Service between 2001 and 2008.

MATERIALS AND METHODS

Demographical data, clinical presentation, investigations as well as the treatment of sixteen JNA patients were reviewed and collected from medical records from the ORL Service.

DESIGN

Cross-sectional, retrospective and descriptive study.

RESULTS

All JNA patients were male. The average age at diagnosis was 16.8 years (range 9-23 years). More than 56% of the patients were classified as Fisch II. Preoperative embolization was carried out in ten (62.5%) patients. All 16 patients were submitted to primary surgical resection. Two patients (66.7%) who didn't receive preoperative embolization required intraoperative blood transfusion. The overall recurrence rate was 43.75% and the cure rate was 93.75%.

CONCLUSION

Preoperative embolization minimizes intraoperative blood loss. The recurrence rate was related to advanced tumoral stage at diagnostic and the lack of preoperative embolization. Surgery combined with preoperative embolization is the major treatment for JNA. All the patients should undergo preoperative imaging studies, especially CT, to assist in surgical planning and follow-up.

摘要

未注明

青少年鼻咽血管纤维瘤(JNA)是青少年男性中罕见的肿瘤。它起源于鼻咽部。

目的

介绍 2001 年至 2008 年耳鼻喉科服务中 JNA 管理的经验。

材料和方法

从耳鼻喉科服务的病历中回顾和收集了 16 例 JNA 患者的人口统计学数据、临床表现、检查以及治疗情况。

设计

横断面、回顾性和描述性研究。

结果

所有 JNA 患者均为男性。诊断时的平均年龄为 16.8 岁(范围 9-23 岁)。超过 56%的患者被归类为 Fisch II 期。10 例(62.5%)患者进行了术前栓塞。16 例患者均接受了原发性手术切除。未接受术前栓塞的 2 例患者(66.7%)需要术中输血。总的复发率为 43.75%,治愈率为 93.75%。

结论

术前栓塞可减少术中失血量。复发率与诊断时肿瘤晚期以及缺乏术前栓塞有关。手术联合术前栓塞是 JNA 的主要治疗方法。所有患者均应进行术前影像学检查,尤其是 CT,以协助手术计划和随访。

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