Fonseca Adriano Santana, Vinhaes Eriko, Boaventura Viviane, Andrade Nilvano Alves de, Dias Lislane Andrade, Medeiros Vyrna, Coifman Fernando
Santa Casa de Misericórdia da Bahia, Hospital Santa Izabel.
Braz J Otorhinolaryngol. 2008 Jul-Aug;74(4):583-7. doi: 10.1016/s1808-8694(15)30607-8.
Juvenile nasopharyngeal angiofibroma (JNA) is an uncommon tumor of the sphenopalatine foramen. Surgery combined with preoperative embolization has been the treatment of choice for JNA patients without intracranial invasion. This study aims to assess the viability of surgically treating non-embolized patients with JNA (types I-III according to Fisch).
This is a retrospective, descriptive study based on the medical records of 15 patients with histologically confirmed JNA (Fisch's types I- III), who underwent surgical treatment without pre-op embolization in our institution between 2000 and 2005.
Seven of the fifteen patients were approached endoscopically, four through the transantral approach, three were treated with the combined transmaxillary and endoscopic approach, and one with the combined transmaxillary and transpalatal approach. Six patients required intraoperatory blood transfusion, averaging volumes of 1.3 unit/patient. There were no cases of death or significant morbidity. Eleven of the fifteen patients were followed for an average of twelve months and 27% of them relapsed. Four patients did not comply with the follow-up scheme.
Resection of JNF types I-III was safely completed in non-embolized patients. The observed levels of intraoperative bleeding, occurrence of complications, and rates of recurrence were close to those seen in embolized patients as found in the literature.
青少年鼻咽血管纤维瘤(JNA)是一种罕见的蝶腭孔肿瘤。手术联合术前栓塞一直是无颅内侵犯的JNA患者的首选治疗方法。本研究旨在评估手术治疗未经栓塞的JNA患者(根据Fisch分类为I - III型)的可行性。
这是一项回顾性描述性研究,基于2000年至2005年间在我们机构接受手术治疗且未进行术前栓塞的15例组织学确诊为JNA(Fisch I - III型)患者的病历。
15例患者中,7例采用内镜入路,4例经经鼻窦入路,3例采用经上颌窦和内镜联合入路,1例采用经上颌窦和经腭联合入路。6例患者术中需要输血,平均输血量为1.3单位/患者。无死亡或严重并发症病例。15例患者中有11例平均随访12个月,其中27%复发。4例患者未遵守随访方案。
在未经栓塞的患者中,I - III型JNF的切除安全完成。观察到的术中出血水平、并发症发生率和复发率与文献中栓塞患者的情况相近。