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子宫平滑肌肉瘤转移至胰腺:一例报告并文献复习

Uterine leiomyosarcoma metastasis to the pancreas: report of a case and review of the literature.

作者信息

Alonso Gómez Jaime, Arjona Sánchez Álvaro, Martínez Cecilia David, Díaz Nieto Rafael, Roldán de la Rúa Jorge, Valverde Martínez Amparo, Lizárraga Febres Enrique, Padillo Ruiz Javier, Rufián Peña Sebastián

机构信息

Hospital Universitario Reina Sofía, Córdoba, Spain.

出版信息

J Gastrointest Cancer. 2012 Jun;43(2):361-3. doi: 10.1007/s12029-010-9172-x.

DOI:10.1007/s12029-010-9172-x
PMID:20549388
Abstract

INTRODUCTION

Uterine leiomyosarcoma is an aggressive malignant tumor that often leads to metastatic dissemination, generally in the lungs, liver, brain, and bones. Despite the fact that pancreatic neoplasms spread easily, the pancreas is not a usual target organ from other neoplasms.

CASE REPORT

We present a rare case of metastasis to the pancreas from uterine leiomyosarcoma treated with segmental resection with no recurrence at this stage. A review of the literature is later presented showing no similar case to what has been reported.

DISCUSSION

Surgical resection of unique pancreatic metastases is a safe practice. An increase in the survival rate has been demonstrated after resection of metastases from renal cell carcinoma, although it has not been proved with metastases from other locations. Further trials are needed.

摘要

引言

子宫平滑肌肉瘤是一种侵袭性恶性肿瘤,常导致转移扩散,通常转移至肺、肝、脑和骨骼。尽管胰腺肿瘤易于扩散,但胰腺并非其他肿瘤常见的转移靶器官。

病例报告

我们报告一例罕见的子宫平滑肌肉瘤转移至胰腺的病例,该病例接受了节段性切除治疗,目前尚无复发。随后对文献进行了回顾,结果显示没有与本报告类似的病例。

讨论

对孤立性胰腺转移瘤进行手术切除是一种安全的做法。肾细胞癌转移瘤切除术后生存率有所提高,尽管其他部位转移瘤切除术后生存率尚未得到证实。还需要进一步的试验。

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Ann Surg Oncol. 2008 Nov;15(11):3199-206. doi: 10.1245/s10434-008-0140-7. Epub 2008 Sep 11.
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One-stage surgery of low-grade malignant intravenous uterine leiomyosarcomatosis with right atrium extension.伴有右心房受累的低度恶性子宫静脉平滑肌瘤病一期手术。
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Pancreatic metastasis from renal cell carcinoma 16 years after nephrectomy: a case report and review of the literature.
复发性阔韧带平滑肌肉瘤伴胰腺及大腿转移:一例报告
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Multidetector computed tomography features of pancreatic metastases from leiomyosarcoma: Experience at a tertiary cancer center.平滑肌肉瘤胰腺转移的多排螺旋计算机断层扫描特征:一家三级癌症中心的经验
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MMPs and angiogenesis affect the metastatic potential of a human vulvar leiomyosarcoma cell line.基质金属蛋白酶(MMPs)与血管生成影响人外阴平滑肌肉瘤细胞系的转移潜能。
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