Morikawa Hiromasa, Tanaka Toru, Hamaji Masatsugu, Ueno Yoichiro, Hara Akira
Department of General Thoracic Surgery, National Hospital Organization Nagara Medical Center, Gifu, Japan.
Gen Thorac Cardiovasc Surg. 2010 Jun;58(6):295-7. doi: 10.1007/s11748-009-0518-x. Epub 2010 Jun 13.
In this report, we describe a case of a thymic carcinoma that developed in a thymic cyst, which was resected by video-assisted thoracic surgery (VATS). Chest radiography of a 68-year-old Japanese woman revealed an abnormal shadow. She was asymptomatic with normal physical examination findings. Chest computed tomography demonstrated a well-confined cystic mass that measured 4 cm in diameter occupying the anterior mediastinum. Based on these findings, a thymic cyst was suspected. It was completely resected by VATS. The excised cyst was multiloculated with a partially thick wall. Microscopic examination revealed that the nodular excrescence of the wall to be limited to papillary adenocarcinoma and the cyst wall to be lined by cuboidal cells. On the basis of this diagnosis, we performed multidrug adjuvant chemotherapy. The patient was alive without any sign of recurrence 15 months after the operation.
在本报告中，我们描述了一例发生于胸腺囊肿的胸腺癌病例，该病例通过电视辅助胸腔镜手术（VATS）进行了切除。一名68岁日本女性的胸部X线检查显示有异常阴影。她没有症状，体格检查结果正常。胸部计算机断层扫描显示一个边界清晰的囊性肿块，直径4厘米，占据前纵隔。基于这些发现，怀疑为胸腺囊肿。通过VATS将其完全切除。切除的囊肿为多房性，部分囊壁增厚。显微镜检查显示，壁上的结节状赘生物局限于乳头状腺癌，囊壁由立方细胞内衬。基于这一诊断，我们进行了多药辅助化疗。患者术后15个月存活，无任何复发迹象。
