Mitry Danny, Charteris David G, Yorston David, Siddiqui M A Rehman, Campbell Harry, Murphy Anna-Louise, Fleck Brian W, Wright Alan F, Singh Jaswinder
Princess Alexandra Eye Pavilion, Edinburgh, Scotland, UK.
Invest Ophthalmol Vis Sci. 2010 Oct;51(10):4963-8. doi: 10.1167/iovs.10-5400. Epub 2010 Jun 16.
Rhegmatogenous retinal detachment (RRD) is a common ophthalmic emergency. Population-based data on primary RRD incidence has been variable, with large differences reported. This study is the first large-scale prospective examination of the incidence of primary RRD in the United Kingdom.
The authors established a two-year prospective, population-based observational study recruiting all cases of primary RRD in Scotland. The annual incidence was calculated and analyzed in relation to age, sex, refractive error, and lens status. A national, population-based tool, the Scottish Index of Multiple Deprivation (SIMD), was used to examine the socioeconomic distribution of all incident cases.
A total of 1244 cases were identified during the study period from a population of 5,168,500 yielding an annual incidence of 12.05 per 100,000 population (95% confidence interval, 11.35-12.70). The age-specific incidence increased to a peak in both sexes in the 60- to 69-year age group. RRD was significantly more frequent in males than in females (14.70 vs. 8.75 per 100,000; P < 0.001). Of the cases without previous intraocular surgery, 53.2% were myopic, with a spherical equivalent refractive error > -1 D, 23.4% had undergone cataract surgery, and 10.4% had sustained traumatic injury. A strong association was found between RRD incidence and affluence, with a significant rising trend across quintiles of deprivation.
The estimated annual incidence of primary RRD in Scotland is 12.05 per 100,000. Based on this estimate, there are approximately 7300 new cases annually in the United Kingdom. RRD incidence increases with age, is more common in men and right eyes, and is strongly associated with affluence.
孔源性视网膜脱离(RRD)是一种常见的眼科急症。基于人群的原发性RRD发病率数据存在差异,报道的差异很大。本研究是对英国原发性RRD发病率进行的首次大规模前瞻性研究。
作者开展了一项为期两年的基于人群的前瞻性观察性研究,招募了苏格兰所有原发性RRD病例。计算并分析了年发病率与年龄、性别、屈光不正和晶状体状态的关系。使用基于全国人群的工具——苏格兰多重贫困指数(SIMD)来研究所有发病病例的社会经济分布情况。
在研究期间,从5168500人的人群中识别出1244例病例,年发病率为每10万人12.05例(95%置信区间,11.35 - 12.70)。特定年龄发病率在60至69岁年龄组中男女均升至峰值。RRD在男性中比在女性中明显更常见(每10万人分别为14.70例和8.75例;P < 0.001)。在没有既往眼内手术的病例中,53.2%为近视,等效球镜屈光不正 > -1 D,23.4%接受过白内障手术,10.4%有过外伤。发现RRD发病率与富裕程度之间存在密切关联,贫困程度五分位数间呈显著上升趋势。
苏格兰原发性RRD的估计年发病率为每10万人12.05例。基于这一估计,英国每年约有7300例新病例。RRD发病率随年龄增加,在男性和右眼更常见,且与富裕程度密切相关。