Hebert Kathy, Lopez Barbara, Michael Christina, Franco Emiliana, Dias Andre, Trahan Pat, Huang Shi, Tamariz Leonardo, Arcement Lee
Cardiovascular Division, Miller School of Medicine, University of Miami, Jackson Memorial Hospital, Miami, FL 33136, USA.
Congest Heart Fail. 2010 May-Jun;16(3):118-21. doi: 10.1111/j.1751-7133.2010.00140.x.
More than 5 million people live with heart failure (HF) in the United States, and this number is expected to rise due to several factors including increased life expectancy brought about by medical therapy and the aging of the population. HF and peripheral arterial disease (PAD) share many risk factors. A review of the literature reveals several studies supporting a higher prevalence of HF in patients with PAD than in those without PAD. However, no study was found that estimates the prevalence of PAD in patients with HF. Moreover, the prevalence of PAD by US race/ethnic groups with HF has not been studied. The authors conducted a cross-sectional multicenter study of patients enrolled in an HF disease management program in Louisiana (n=330) and Florida (n=464). All patients with an ejection fraction <or=40% and a measured ankle-brachial index (ABI) were included in the study. PAD was defined as an ABI <0.9. The overall prevalence of PAD was 17.1%. The prevalence of PAD was 25.9% for white, 13.4% for Hispanic, and 13.7% for black patients. White patients had a higher prevalence of PAD than black or Hispanic patients (P<.001). Routine ABI measurements in these groups would enhance efforts to detect subclinical PAD.
在美国,有超过500万人患有心力衰竭(HF),由于多种因素,包括医学治疗带来的预期寿命延长和人口老龄化,这一数字预计还会上升。HF和外周动脉疾病(PAD)有许多共同的危险因素。文献综述显示,多项研究支持PAD患者中HF的患病率高于无PAD患者。然而,未发现有研究估计HF患者中PAD的患病率。此外,HF患者中按美国种族/族裔划分的PAD患病率尚未得到研究。作者对路易斯安那州(n = 330)和佛罗里达州(n = 464)参加HF疾病管理项目的患者进行了一项横断面多中心研究。所有射血分数≤40%且测量了踝臂指数(ABI)的患者均纳入研究。PAD定义为ABI<0.9。PAD的总体患病率为17.1% 。白人患者中PAD的患病率为25.9%,西班牙裔为13.4%,黑人患者为13.7%。白人患者中PAD的患病率高于黑人或西班牙裔患者(P<0.001)。对这些人群进行常规ABI测量将有助于加强对亚临床PAD的检测。