Centre for Cardiovascular and Chronic Care, Faculty of Nursing, Midwifery and Health, University of Technology Sydney, PO BOX 123, Broadway, 235 Jones Street, Ultimo, Sydney, NSW 2007, Australia.
Heart Fail Rev. 2013 Jul;18(4):457-64. doi: 10.1007/s10741-012-9331-1.
Chronic heart failure (CHF) is associated with a high comorbidity burden, adverse impact on quality of life and high health care utilisation. Peripheral arterial disease (PAD) and CHF share many risk, pathophysiological and prognostic features, and each has been associated with increased morbidity and mortality. PAD often goes undetected, and yet in spite of the availability of screening tools, this is not commonly considered in CHF care. A review of the electronic databases Medline, CINAHL and Cochrane CENTRAL was undertaken using the MeSH terms peripheral arterial disease, peripheral vascular disease, intermittent claudication and heart failure to identify studies examining the prevalence and clinical outcomes of coexisting PAD in patients with CHF. Five studies were identified. There are limited data describing the impact of PAD on CHF outcomes. As PAD may contribute to decreased capacity to exercise and other self-care behaviours, identifying those at risk and providing appropriate therapy are important. Based on this review, patients who are smokers and those with diagnosed coronary heart disease and diabetes should be targeted for the screening of PAD.
慢性心力衰竭（CHF）与高合并症负担、生活质量下降和高医疗保健利用率相关。外周动脉疾病（PAD）和 CHF 具有许多共同的风险、病理生理和预后特征，并且两者都与发病率和死亡率增加相关。PAD 常常未被发现，尽管有筛查工具，但在 CHF 护理中通常不考虑这一点。使用 MeSH 术语外周动脉疾病、周围血管疾病、间歇性跛行和心力衰竭，对 Medline、CINAHL 和 Cochrane CENTRAL 电子数据库进行了审查，以确定检查 CHF 患者并存 PAD 的患病率和临床结局的研究。确定了五项研究。描述 PAD 对 CHF 结局影响的数据有限。由于 PAD 可能导致运动能力下降和其他自我护理行为减少，因此识别高危人群并提供适当的治疗非常重要。基于这篇综述，应针对吸烟者以及诊断为冠心病和糖尿病的患者进行 PAD 筛查。
