Department of Psychology and the Gonda Brain Sciences Center, Bar-Ilan University, Ramat-Gan, Israel.
Horm Behav. 2010 Sep;58(4):669-76. doi: 10.1016/j.yhbeh.2010.06.005. Epub 2010 Jun 15.
Animal studies demonstrated that the neuropeptide oxytocin (OT), implicated in bond formation across mammalian species, is transmitted from mother to young through mechanisms of early social experiences; however, no research has addressed the cross-generation transmission of OT in humans. Fifty-five parents (36 mothers and 19 fathers) engaged in a 15-min interaction with their infants. Baseline plasma OT was sampled from parents and salivary OT was sampled from parents and infants before and after play and analyzed with ELISA methods. Interactions were micro-coded for parent and child's socio-affective behavior. Parent and infant's salivary OT was individually stable across assessments and showed an increase from pre- to post-interaction. Significant correlations emerged between parental and infant OT at both assessments and higher OT levels in parent and child were related to greater affect synchrony and infant social engagement. Parent-infant affect synchrony moderated the relations between parental and infant OT and the associations between OT in parent and child were stronger under conditions of high affect synchrony. Results demonstrate consistency in the neuroendocrine system supporting bond formation in humans and other mammals and underscore the role of early experience in shaping the cross-generation transmission of social affiliation in humans.
动物研究表明，神经肽催产素（OT）在跨哺乳动物物种的结合中起作用，通过早期社会经验的机制从母亲传递给幼崽；然而，目前还没有研究探讨 OT 在人类中的跨代传递。55 名父母（36 名母亲和 19 名父亲）与他们的婴儿进行了 15 分钟的互动。在玩耍前后，从父母身上采集基础血浆 OT，从父母和婴儿身上采集唾液 OT，并使用 ELISA 方法进行分析。互动被微编码为父母和孩子的社会情感行为。父母和婴儿的唾液 OT 在各项评估中均具有个体稳定性，并在互动前到互动后有所增加。在两项评估中都出现了父母和婴儿 OT 之间的显著相关性，并且父母和孩子的 OT 水平越高，与更大的情感同步和婴儿的社会参与度越高相关。父母-婴儿的情感同步调节了父母和婴儿之间的 OT 关系，并且在高情感同步条件下，父母和孩子之间的 OT 关联更强。结果表明，支持人类和其他哺乳动物结合的神经内分泌系统具有一致性，并强调了早期经验在塑造人类社会联系的跨代传递中的作用。
