Department of Advanced Hybrid Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan.
Graduate School of Education, Kyoto University, Kyoto, Japan.
Commun Biol. 2024 Feb 29;7(1):235. doi: 10.1038/s42003-024-05884-5.
The number of mothers suffering from mental illness is increasing steadily, particularly under conditions of the coronavirus pandemic. The identification of factors that contribute to resilience in mothers is urgently needed to decrease the risks of poor physical and psychological health. We focused on the risk of parenting stress and psychological resilience in healthy mothers with no psychiatric and physical disorders and conducted two studies to examine the relationships between intestinal microbiota, physical condition, and psychological state. Our results showed that alpha diversity and beta diversity of the microbiome are related to high parenting stress risk. Psychological resilience and physical conditions were associated with relative abundances of the genera Blautia, Clostridium, and Eggerthella. This study helps further understand the gut-brain axis mechanisms and supports proposals for enhancing resilience in mothers.
患有精神疾病的母亲人数在稳步增加，尤其是在冠状病毒大流行的情况下。迫切需要确定导致母亲具有韧性的因素，以降低身体健康和心理健康不良的风险。我们关注的是没有精神和身体障碍的健康母亲的育儿压力和心理弹性风险，并进行了两项研究来检验肠道微生物群、身体状况和心理状态之间的关系。我们的结果表明，微生物组的 alpha 多样性和 beta 多样性与高育儿压力风险有关。心理弹性和身体状况与 Blautia、Clostridium 和 Eggerthella 属的相对丰度有关。这项研究有助于进一步了解肠道-大脑轴机制，并支持增强母亲韧性的建议。
