Jiangsu Key Laboratory of Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing 210029, China.
Fitoterapia. 2010 Oct;81(7):932-6. doi: 10.1016/j.fitote.2010.06.009. Epub 2010 Jun 15.
The reinvestigation of Strychnos nux-vomica resulted in the isolation of two colorless monoquaternary bisindole alkaloids from the seeds. The structures of the two new compounds named 4-N-hydroxymethyl strychnidin-17-acetic acid (1) and 10, 11-dimethoxy-4-N-hydroxymethyl strychnidin-17-acetic acid (2), were defined by detailed spectral analyses, especially (1)H NMR, (13)C NMR, DEPT, HSQC, (1)H NMR-(1)H NMR, NOESY, HMBC and TOF-MS.
对马钱子的再研究从种子中分离得到两种无色单季铵双吲哚生物碱。通过详细的光谱分析,特别是 1H NMR、13C NMR、DEPT、HSQC、1H NMR-1H NMR、NOESY、HMBC 和 TOF-MS,确定了这两个新化合物的结构,分别命名为 4-N-羟甲基士的宁-17-乙酸(1)和 10,11-二甲氧基-4-N-羟甲基士的宁-17-乙酸(2)。