School of Pharmacy, University of Otago, 18 Frederick Street, Dunedin 9054, Otago, New Zealand.
Age Ageing. 2010 Sep;39(5):574-80. doi: 10.1093/ageing/afq069. Epub 2010 Jun 17.
older people experience more chronic medical conditions than younger people, take more prescription medicines and are more likely to suffer from cognitive or memory problems. Older people are more susceptible to the adverse effects of medicines, which may reduce their quality of life or lead to hospitalisation or death.
this study aims to identify medicine-taking practices amongst community-dwelling people aged > or =75 years in New Zealand.
this study was carried out in an urban setting in Dunedin (population 120,000), New Zealand. Interviews of a random sample of people from the electoral roll using a structured questionnaire were conducted. Subjects were community-dwelling people aged > or =75 years taking one or more prescription medicines. From a random sample of 810 people extracted from the electoral roll intended to recruit 300 participants, 524 people met the study criteria and were invited to participate. People living in a rest home or hospital, not contactable by telephone, or now deceased, were excluded. Responses were analysed, medicines categorised by the Anatomical Therapeutic Chemical classification and adherence classed as high, medium and low using a modified four-item Morisky Medication Adherence Scale. Univariate and multivariate linear and logistic regression was applied to combinations of variables.
in total, 316 interviews were undertaken; a 61% response rate. Participants were 75-79 (35%), 80-84 (40%) and >85 years (25%); New Zealand European/European (84%), 'New Zealanders' (14%) or Maori (2%); and 141 (45%) lived alone. Almost half (49%) regularly saw a specialist and a third (34%) had been admitted to hospital in the past 12 months. Participants used a median of seven prescription medicines (range 1-19) and one non-prescription medicine (0-14). The majority (58%) believed medicines are effective and had systems/routines (92%) for remembering to take them. Doses tended to be missed following a change in routine, e.g. holiday. Men were more likely to report 'trouble remembering' than women (odds ratio = 1.86, 95% confidence interval 1.10-3.14; P = 0.020). Seventy-five percent of people had high or medium adherence scores and 25%, low scores. Common problems were reading and understanding labels (9 and 4%, respectively) and leaflets (12%, 6%), and difficulty swallowing solid dose forms (14%). Only 6% had problems paying for their medicines. Around 17% wanted to know more about their medicines, and some people were confused about their medicines following hospital discharge.
overall, community-dwelling people aged > or =75 years in this study appeared to manage their medicines well and found them affordable. Nevertheless, there is a need to improve labelling, leaflets and education on medicines, particularly at hospital discharge.
老年人比年轻人更容易患慢性疾病,服用更多的处方药,并且更容易出现认知或记忆问题。老年人更容易受到药物的不良影响,这可能会降低他们的生活质量,或导致住院或死亡。
本研究旨在确定新西兰 75 岁及以上社区居民的用药情况。
本研究在新西兰达尼丁(人口 12 万)的城市环境中进行。采用结构化问卷对从选民名单中随机抽取的人群进行访谈。研究对象为服用一种或多种处方药的 75 岁及以上社区居民。从选民名单中随机抽取了 810 人作为随机样本,计划招募 300 名参与者,其中 524 人符合研究标准并被邀请参加。排除住在养老院或医院、无法通过电话联系或已去世的人。对受访者进行分析,根据解剖治疗化学分类对药物进行分类,并使用改良的四项 Morisky 药物依从性量表将药物分类为高、中、低依从性。采用单变量和多变量线性和逻辑回归分析各种变量的组合。
共进行了 316 次访谈,应答率为 61%。参与者年龄为 75-79 岁(35%)、80-84 岁(40%)和>85 岁(25%);新西兰欧洲/欧洲裔(84%)、“新西兰人”(14%)或毛利人(2%);141 人(45%)独居。近一半(49%)的人定期看专科医生,三分之一(34%)的人在过去 12 个月内住院。参与者平均使用七种处方药(范围 1-19)和一种非处方药(0-14)。大多数(58%)人认为药物有效,并制定了(92%)有系统/常规来记住服药。剂量往往在日常生活规律改变时(例如假期)漏服。男性比女性更有可能报告“难以记住”(优势比=1.86,95%置信区间 1.10-3.14;P=0.020)。75%的人有高或中依从性评分,25%的人有低依从性评分。常见的问题是阅读和理解标签(分别为 9%和 4%)和传单(12%,6%),以及吞咽固体剂型困难(14%)。只有 6%的人在支付药品费用方面有困难。大约 17%的人希望了解更多关于他们的药物信息,一些人在出院后对他们的药物感到困惑。
总体而言,本研究中 75 岁及以上的社区居民似乎能够很好地管理他们的药物,并且他们认为药物负担得起。然而,仍有必要改善药物标签、传单和教育,特别是在出院时。