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老年人视角下与药物治疗相关的负担

Medication-related burden from the perspective of the elderly.

作者信息

Alqallaf Sayed Mahmood, Matar Layan, Ghuloom Kawthar, Alabbad Kawthar, Alshaikh Fatema, Alhaddad Mustafa

机构信息

Pharmacy Department, Salmaniya Medical Complex, College of Health and Sport Sciences, Kingdom of Bahrain.

出版信息

Med Pharm Rep. 2022 Jul;95(3):320-331. doi: 10.15386/mpr-2133. Epub 2022 Jul 26.

Abstract

BACKGROUND AND AIMS

Extensive polypharmacy in the elderly population affects their quality of life and medication compliance. The UK-developed LMQ-3 (Living with Medicine Questionnaire-3) is a valid instrument designed to quantify medicine burden.The aims of this study were to assess the medication-related burden among Bahraini elderly population in relation to their medication consumption patterns and other socio-demographic characteristics and identify specific issues that need to be addressed from the responses.

METHODS

The descriptive cross-sectional study was designed to interview 500 Bahrainis over 65 years of age, by using an LMQ-3 questionnaire. Sample size was determined by Slovin's formula. Data on socio-demographic characteristics and medication consumption patterns were collected, then LMQ-3 and domain scores were compared by patient characteristics using descriptive statistics and statistical tests.

RESULTS

We found a wide range of burden among participants in Bahrain, ranging from moderate burden in almost a third of participants, to high burden, over two- thirds of participants. Burden was mainly driven by concerns about medicines, interferences of medicines with daily life and side effects. Higher LMQ-3 scores were associated with those who were technical colleges graduates (7.5, p<0.001), aged ≥75 years (7.7, p<0.001), using ≥9 medicines (7.4, p<0.001), or using medicines four times a day (7.5, p<0.001). Anti-diabetics were the most prescribed medicines for the elderly.

IN CONCLUSION

high medication related burden was observed in the majority of patients with the highest seen in certain categories of participants such as the employed and the technical college graduates. Patients with the highest medication related burden should become the main target for practitioners and pharmacists.

摘要

背景与目的

老年人群中广泛的多重用药会影响他们的生活质量和用药依从性。英国开发的LMQ-3(生活与用药问卷-3)是一种用于量化用药负担的有效工具。本研究的目的是评估巴林老年人群中与用药相关的负担,及其用药消费模式和其他社会人口学特征,并从回答中确定需要解决的具体问题。

方法

本描述性横断面研究旨在通过使用LMQ-3问卷对500名65岁以上的巴林人进行访谈。样本量由斯洛文公式确定。收集了社会人口学特征和用药消费模式的数据,然后使用描述性统计和统计检验按患者特征比较LMQ-3及其领域得分。

结果

我们发现巴林的参与者中存在广泛的负担,从近三分之一参与者的中度负担到超过三分之二参与者的高度负担。负担主要由对药物的担忧、药物对日常生活的干扰和副作用驱动。较高的LMQ-3得分与技术学院毕业生(7.5,p<0.001)、年龄≥75岁(7.7,p<0.001)、使用≥9种药物(7.4,p<0.001)或每天用药四次(7.5,p<0.001)的人相关。抗糖尿病药物是老年人最常开具的药物。

结论

在大多数患者中观察到较高的用药相关负担,在某些参与者类别中,如就业者和技术学院毕业生中负担最高。用药相关负担最高的患者应成为从业者和药剂师的主要目标。

相似文献

1
Medication-related burden from the perspective of the elderly.老年人视角下与药物治疗相关的负担
Med Pharm Rep. 2022 Jul;95(3):320-331. doi: 10.15386/mpr-2133. Epub 2022 Jul 26.

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An overview of prevalence, determinants and health outcomes of polypharmacy.多重用药的患病率、决定因素及健康结果概述。
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