Calabrese Edward J, Jonas Wayne B
Environmental Health Sciences Program, School of Public Health, University of Massachusetts, Amherst, Massachusetts 01003, USA.
Hum Exp Toxicol. 2010 Jul;29(7):531-6. doi: 10.1177/0960327110369857.
This paper presents the case that certain types of homeopathic medicine may represent a form of hormesis, that is, either pre- or post-conditioning hormesis. An example of a post-conditioning model by van Wijk and colleagues demonstrated successful enhancement of adaptive responses using below-toxic threshold doses (i.e. hormetic doses) of inducing agents when administered subsequent to a highly toxic chemical exposure, thus satisfying a basic experimental biomedical standard. Of note is that this model uses exposures within a measurable predicted hormetic range, unlike most forms of homeopathy. This experimental framework (along with a pre-conditioning model developed by Bellavite) provides a possible vehicle by which certain aspect(s) of homeopathy may be integrated into mainstream biomedical assessment and clinical practice.
本文提出这样一种观点，即某些类型的顺势疗法药物可能代表一种兴奋效应形式，也就是预处理或后处理兴奋效应。范·维克及其同事提出的一个后处理模型示例表明，在高毒性化学物质暴露之后给予低于毒性阈值剂量（即兴奋剂量）的诱导剂，能够成功增强适应性反应，从而满足基本的实验生物医学标准。值得注意的是，该模型使用的暴露剂量处于可测量的预测兴奋效应范围内，这与大多数顺势疗法形式不同。这个实验框架（以及贝拉维特提出的预处理模型）为顺势疗法的某些方面融入主流生物医学评估和临床实践提供了一种可能的途径。
