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Fournier 坏疽:80 例患者分析及一种新的评分系统。

Fournier's gangrene: an analysis of 80 patients and a novel scoring system.

机构信息

Department of General Surgery, Uludag University School of Medicine, Gorukle, 16069 Bursa, Turkey.

出版信息

Tech Coloproctol. 2010 Sep;14(3):217-23. doi: 10.1007/s10151-010-0592-1. Epub 2010 Jun 18.

Abstract

BACKGROUND

To create a better scoring system for outcome prediction for patients with Fournier's gangrene in order to design more appropriate and feasible management strategies.

METHODS

Using logistic regression, the medical records of 80 patients who underwent surgery for Fournier's gangrene in the last 10 years were reviewed using a prospectively maintained database, and a novel scoring system was adopted combining this data with the Fournier's gangrene severity index (FGSI). The new system consists of a physiological score, an age score, and an extent of gangrene score.

RESULTS

The mortality rate of the 80 patients was 21%. Using the new scoring system (UFGSI), at a threshold value of 9, there was a 94% probability of death with a score greater than 9 and an 81% probability of survival with a score of 9 or less (P < 0.001). The receiver operating characteristics (ROC) analysis concluded that the new scoring system was more powerful than the FGSI (P = 0.002).

CONCLUSIONS

The power of the novel scoring system introduced in this study proves that in patients with Fournier's gangrene, the extent of the gangrene as well as the patient's age and physiological status have a significant effect on the outcome.

摘要

背景

为了创建一个更好的 Fournier 坏疽患者预后评分系统,以便设计更合适和可行的管理策略。

方法

使用逻辑回归,通过前瞻性维护的数据库,回顾了过去 10 年中 80 名接受 Fournier 坏疽手术的患者的病历,并采用了一种新的评分系统,该系统将数据与 Fournier 坏疽严重指数(FGSI)相结合。新系统由生理评分、年龄评分和坏疽程度评分组成。

结果

80 名患者的死亡率为 21%。使用新的评分系统(UFGSI),在阈值为 9 时,评分大于 9 的患者死亡概率为 94%,评分等于或小于 9 的患者生存概率为 81%(P < 0.001)。接收者操作特征(ROC)分析表明,新的评分系统比 FGSI 更有效(P = 0.002)。

结论

本研究中引入的新评分系统的有效性证明,在 Fournier 坏疽患者中,坏疽的程度以及患者的年龄和生理状况对结果有重大影响。

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