Department of Paediatric Haematology, King's College London School of Medicine, King's College Hospital, Denmark Hill, London, UK.
Br J Haematol. 2010 Sep;150(5):614-7. doi: 10.1111/j.1365-2141.2010.08272.x. Epub 2010 Jun 15.
We retrospectively audited children with sickle cell disease (SCD) admitted to paediatric intensive care (PICU) at King's College Hospital between January 2000 and December 2008. Forty-six children with SCD were admitted, on 49 separate occasions. Ages ranged from 4 months to 15 years (median 7.6 years). Three children died in PICU, however two presented to hospital in cardiorespiratory arrest; overall mortality was 6%. The most common reason for admission was acute chest syndrome (43%). 88% of admissions required blood transfusion, of which 74% had exchange blood transfusions. The mortality among children with SCD admitted to PICU is low.
我们回顾性审核了 2000 年 1 月至 2008 年 12 月期间在国王学院医院儿科重症监护病房（PICU）住院的镰状细胞病（SCD）患儿。共有 46 名 SCD 患儿，49 次单独入院。年龄从 4 个月到 15 岁不等（中位数为 7.6 岁）。3 名儿童在 PICU 死亡，但其中 2 名在心肺骤停时就诊；总体死亡率为 6%。最常见的入院原因是急性胸部综合征（43%）。88%的入院患儿需要输血，其中 74%接受了换血治疗。入住 PICU 的 SCD 患儿死亡率较低。
