Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, Denmark Hill, London, UK.
Br J Haematol. 2010 Sep;150(5):610-3. doi: 10.1111/j.1365-2141.2010.08271.x. Epub 2010 Jun 15.
Sickle cell disease (SCD) patients are perceived to have a high mortality when admitted to the Critical Care Unit (CCU). We performed a retrospective analysis of all adult sickle admissions to CCU at a single centre over an 8-year period (1 January 2000 to 31 December 2007). Thirty-eight patients (14 male) were admitted 46 times to CCU; the commonest reasons for admission were acute chest syndrome (14, 30%), multi-organ failure (8, 17%) and planned post-elective surgery (7, 15%). CCU mortality for SCD patients was 19.6%, comparable to a CCU-wide mortality of 17.6% during the study period in the same institution. Re-admission to CCU was high (16% over the 8-year period) but did not increase mortality risk.
镰状细胞病（SCD）患者在入住重症监护病房（CCU）时被认为死亡率较高。我们对单一中心 8 年来（2000 年 1 月 1 日至 2007 年 12 月 31 日）所有成年镰状细胞患者入住 CCU 的情况进行了回顾性分析。38 名患者（14 名男性）46 次入住 CCU；最常见的入院原因是急性胸部综合征（14 例，30%）、多器官衰竭（8 例，17%）和计划择期手术后（7 例，15%）。SCD 患者的 CCU 死亡率为 19.6%，与同期同一机构 CCU 的 17.6%的死亡率相当。8 年内 CCU 再次入院率较高（16%），但并未增加死亡风险。
