从基因组层面看B细胞的特化。 - Suppr

B cell specification from the genome up.

作者信息

Rothenberg Ellen V

出版信息

Nat Immunol. 2010 Jul;11(7):572-4. doi: 10.1038/ni0710-572.

DOI:10.1038/ni0710-572

PMID:20562842

Abstract

摘要

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本文引用的文献

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate.

Nat Immunol. 2010 Jul;11(7):635-43. doi: 10.1038/ni.1891. Epub 2010 Jun 13.

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities.

Mol Cell. 2010 May 28;38(4):576-89. doi: 10.1016/j.molcel.2010.05.004.

Early B cell factor 1 regulates B cell gene networks by activation, repression, and transcription- independent poising of chromatin.

Immunity. 2010 May 28;32(5):714-25. doi: 10.1016/j.immuni.2010.04.013. Epub 2010 May 6.

Compound haploinsufficiencies of Ebf1 and Runx1 genes impede B cell lineage progression.

Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7869-74. doi: 10.1073/pnas.1003525107. Epub 2010 Apr 12.

Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages.

Immunity. 2010 Mar 26;32(3):317-28. doi: 10.1016/j.immuni.2010.02.008. Epub 2010 Mar 4.

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Curr Opin Immunol. 2010 Apr;22(2):161-7. doi: 10.1016/j.coi.2010.01.010. Epub 2010 Feb 9.

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Semin Immunol. 2008 Aug;20(4):221-7. doi: 10.1016/j.smim.2008.07.004. Epub 2008 Aug 22.

Foxo1 directly regulates the transcription of recombination-activating genes during B cell development.

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Pax5: the guardian of B cell identity and function.

Nat Immunol. 2007 May;8(5):463-70. doi: 10.1038/ni1454.

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B cell specification from the genome up.

Nat Immunol. 2010 Jul;11(7):572-4. doi: 10.1038/ni0710-572.

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate.

Nat Immunol. 2010 Jul;11(7):635-43. doi: 10.1038/ni.1891. Epub 2010 Jun 13.

Complementary regulation of early B-lymphoid differentiation by genetic and epigenetic mechanisms.

Int J Hematol. 2013 Oct;98(4):382-9. doi: 10.1007/s12185-013-1424-7. Epub 2013 Sep 3.

CHD4 is essential for transcriptional repression and lineage progression in B lymphopoiesis.

Proc Natl Acad Sci U S A. 2019 May 28;116(22):10927-10936. doi: 10.1073/pnas.1821301116. Epub 2019 May 13.

HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages.

PLoS Genet. 2013 May;9(5):e1003503. doi: 10.1371/journal.pgen.1003503. Epub 2013 May 16.

Foxo1 regulates marginal zone B-cell development.

Eur J Immunol. 2010 Jul;40(7):1890-6. doi: 10.1002/eji.200939817.

Stage-specific control of early B cell development by the transcription factor Ikaros.

Nat Immunol. 2014 Mar;15(3):283-93. doi: 10.1038/ni.2828. Epub 2014 Feb 9.

FOXO Dictates Initiation of B Cell Development and Myeloid Restriction in Common Lymphoid Progenitors.

Front Immunol. 2022 May 4;13:880668. doi: 10.3389/fimmu.2022.880668. eCollection 2022.

The Justy mutation identifies Gon4-like as a gene that is essential for B lymphopoiesis.

J Exp Med. 2010 Jul 5;207(7):1359-67. doi: 10.1084/jem.20100147. Epub 2010 Jun 7.

EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells.

Mol Cell. 2022 Mar 3;82(5):1003-1020.e15. doi: 10.1016/j.molcel.2022.01.015. Epub 2022 Feb 18.

Characteristics of functional enrichment and gene expression level of human putative transcriptional target genes.

BMC Genomics. 2018 Jan 19;19(Suppl 1):957. doi: 10.1186/s12864-017-4339-5.

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate.

Nat Immunol. 2010 Jul;11(7):635-43. doi: 10.1038/ni.1891. Epub 2010 Jun 13.

Early B cell factor 1 regulates B cell gene networks by activation, repression, and transcription- independent poising of chromatin.

Immunity. 2010 May 28;32(5):714-25. doi: 10.1016/j.immuni.2010.04.013. Epub 2010 May 6.

Compound haploinsufficiencies of Ebf1 and Runx1 genes impede B cell lineage progression.

Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7869-74. doi: 10.1073/pnas.1003525107. Epub 2010 Apr 12.

Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages.

Immunity. 2010 Mar 26;32(3):317-28. doi: 10.1016/j.immuni.2010.02.008. Epub 2010 Mar 4.

Transcription control of early B cell differentiation.

Curr Opin Immunol. 2010 Apr;22(2):161-7. doi: 10.1016/j.coi.2010.01.010. Epub 2010 Feb 9.

Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation.

Nat Immunol. 2008 Dec;9(12):1388-98. doi: 10.1038/ni.1667. Epub 2008 Nov 2.

Early B cell factor: Regulator of B lineage specification and commitment.

Semin Immunol. 2008 Aug;20(4):221-7. doi: 10.1016/j.smim.2008.07.004. Epub 2008 Aug 22.

Foxo1 directly regulates the transcription of recombination-activating genes during B cell development.

Nat Immunol. 2008 Jun;9(6):613-22. doi: 10.1038/ni.1612. Epub 2008 May 11.

Pax5: the guardian of B cell identity and function.

Nat Immunol. 2007 May;8(5):463-70. doi: 10.1038/ni1454.

B cell specification from the genome up.

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