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南卡罗来纳州黑人和白人中宫颈癌与男性口咽癌发病率的联合疾病图谱

Joint disease mapping of cervical and male oropharyngeal cancer incidence in blacks and whites in South Carolina.

作者信息

Onicescu Georgiana, Hill Elizabeth G, Lawson Andrew B, Korte Jeffrey E, Gillespie M Boyd

机构信息

Division of Biostatistics and Epidemiology, Department of Medicine, Medical University of South Carolina, USA.

出版信息

Spat Spatiotemporal Epidemiol. 2010 Jul;1(2-3):133-41. doi: 10.1016/j.sste.2010.03.005.

Abstract

Human papillomavirus (HPV) infection is an established causal agent for cervical cancer and a subset of oropharyngeal cancers. It is hypothesized that orogenital transmission results in oral cavity infection. In this paper we explore the geographical association between cervical and male oropharyngeal cancer incidence in blacks and whites in South Carolina using Bayesian joint disease mapping models fit to publicly available data. Our results suggest weak evidence for county-level association between the diseases, and different patterns of joint disease behavior for blacks and whites.

摘要

人乳头瘤病毒(HPV)感染是宫颈癌和一部分口咽癌的确立病因。据推测,口生殖器传播会导致口腔感染。在本文中,我们使用适合公开可用数据的贝叶斯联合疾病映射模型,探索南卡罗来纳州黑人和白人中宫颈癌与男性口咽癌发病率之间的地理关联。我们的结果表明,两疾病在县级水平上的关联证据薄弱,且黑人和白人的联合疾病行为模式不同。

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