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[大肠杆菌菌株形态变异体特性的比较]

[Comparison of the properties of the morphological variants of E. coli strains].

作者信息

Zalas-Wiecek Patrycja, Gospodarek Eugenia, Kamińska Dorota

机构信息

Katedra i Zakład Mikrobiologii, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Uniwersytetu Mikołaja Kopernika w Toruniu.

出版信息

Med Dosw Mikrobiol. 2010;62(1):51-8.

Abstract

The aim of this study was comparison of the antimicrobial sensitive, adhesive properties and genetic relatedness of the morphological variants of E. coli strains. This study included 10 of E. coli strains isolated in the Clinical Microbiology Department of dr. A. Jurasz University Hospital nr 1 in 2003-2006, which have grown in two morphological variants--light and dark variant. Ninety percent of morphological variants of E. coli strains differed among themselves in antibiotic sensitivity. Forty percent of morphological variants differed among themselves in adhesion to catheters. The light-colony variants more often adhered to all used catheters. The PFGE analysis of chromosomal DNA showed that 35,0% of morphological variants (two pairs and one triple) had 100,0% relatedness, and the rest of them were closely related.

摘要

本研究的目的是比较大肠杆菌菌株形态变体的抗菌敏感性、黏附特性及基因相关性。本研究纳入了2003年至2006年在第一A. 尤拉斯博士大学医院临床微生物科分离出的10株大肠杆菌菌株,这些菌株呈现出两种形态变体——浅色和深色变体。90%的大肠杆菌菌株形态变体在抗生素敏感性方面存在差异。40%的形态变体在对导管的黏附方面存在差异。浅色菌落变体更常黏附于所有使用的导管。染色体DNA的脉冲场凝胶电泳(PFGE)分析表明,35.0%的形态变体(两对和一组三联体)具有100.0%的相关性,其余变体密切相关。

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