Matrajt Mariana
Department of Microbiology and Molecular Genetics, University of Vermont, Stafford Hall, Room 306, 95 Carrigan Drive, Burlington, VT 05405, United States.
Mol Biochem Parasitol. 2010 Nov;174(1):1-7. doi: 10.1016/j.molbiopara.2010.06.002. Epub 2010 Jun 8.
In recent years it has became evident that the transcriptome of most species has little protein-coding capacity and that the abundance of non-coding RNA was previously overlooked. Non-coding RNAs were initially thought to be transcriptional noise, however, a growing number of studies is showing that many of these RNAs have important regulatory functions. Here, we review the progress done in apicomplexan parasites in this rapidly growing field.
近年来,很明显大多数物种的转录组几乎没有蛋白质编码能力,而且非编码RNA的丰度此前被忽视了。非编码RNA最初被认为是转录噪声,然而,越来越多的研究表明,这些RNA中的许多都具有重要的调节功能。在此,我们综述了在这个快速发展的领域中顶复门寄生虫方面所取得的进展。