Saylam Güleser, Tatar Emel Cadalli, Tatar Ilkan, Ozdek Ali, Korkmaz Hakan
Kizilirmak Mah 53.Cad 35/10, 06520-Cukurambar Ankara, Turkey.
Arch Otolaryngol Head Neck Surg. 2010 Jun;136(6):550-5. doi: 10.1001/archoto.2010.70.
To investigate bacterial biofilm formation on the adenoid surface of pediatric patients undergoing adenoidectomy and to reveal whether this formation is associated with chronic otitis media with effusion (COME).
Prospective, single-blinded study with scanning electron microscopy.
Dişkapi Yildirim Beyazit Research and Educational Hospital, Ankara, Turkey.
Thirty-four children between 4 and 15 years of age (mean age, 7.76 years) who had undergone adenoidectomy from June 1 through December 31, 2007, were divided into 2 groups. The first group (17 children) had undergone adenoidectomy alone, whereas the second group (17 children) had undergone adenoidectomy combined with ventilation tube insertion for COME.
Scanning electron microscopy was performed to observe biofilm formation on the surface of adenoid tissues. The biofilm formation was graded according to extension. The roles of adenoid size, age, sex, and duration of COME symptoms were evaluated.
Biofilm formation was detected on all samples. Adenoids removed from patients with COME had higher-grade biofilm formation than the other group (P = .001). No correlation was found between adenoid size and biofilm formation.
In pediatric patients, adenoid surface biofilm formation may be associated with COME etiopathogenesis.
研究接受腺样体切除术的儿科患者腺样体表面细菌生物膜的形成情况，并揭示这种形成是否与慢性分泌性中耳炎（COME）相关。
采用扫描电子显微镜的前瞻性单盲研究。
土耳其安卡拉的迪什卡皮·耶尔德勒姆·贝亚齐特研究与教育医院。
2007年6月1日至12月31日期间接受腺样体切除术的34名4至15岁儿童（平均年龄7.76岁）被分为两组。第一组（17名儿童）仅接受了腺样体切除术，而第二组（17名儿童）接受了腺样体切除术并因COME插入了通气管。
进行扫描电子显微镜观察腺样体组织表面生物膜的形成情况。根据扩展程度对生物膜形成进行分级。评估腺样体大小、年龄、性别和COME症状持续时间的作用。
在所有样本中均检测到生物膜形成。COME患者切除的腺样体生物膜形成等级高于另一组（P = 0.001）。未发现腺样体大小与生物膜形成之间存在相关性。
在儿科患者中，腺样体表面生物膜形成可能与COME的发病机制有关。
