阿魏根提取物对大鼠和豚鼠子宫平滑肌的影响。

Effects of a Ferula sinaica root extract on the uterine smooth muscle of rat and guinea pig.

作者信息

Aqel M B, al-Khalil S, Afifi F

机构信息

Faculty of Medicine, University of Jordan, Amman.

出版信息

J Ethnopharmacol. 1991 Mar;31(3):291-7. doi: 10.1016/0378-8741(91)90014-5.

DOI:10.1016/0378-8741(91)90014-5

PMID:2056757

Abstract

The effects of an ethanolic extract of Ferula sinaica roots on the uterine smooth muscles of rats and guinea pigs were tested in vitro using isolated uterine horns. The extract inhibited the spontaneous movements of rat and guinea pig uterine smooth muscle and also the contractions induced by oxytocin stimulation. These effects were concentration-dependent and reversible by tissue washing. These data suggest that this plant extract may have some antioxytocic potential.

摘要

使用离体子宫角，在体外测试了费拉（Ferula sinaica）根乙醇提取物对大鼠和豚鼠子宫平滑肌的作用。该提取物抑制大鼠和豚鼠子宫平滑肌的自发运动以及催产素刺激诱导的收缩。这些作用呈浓度依赖性，并且通过组织冲洗可逆转。这些数据表明，这种植物提取物可能具有一定的抗催产素潜力。