Aqel M B, al-Khalil S, Afifi F, al-Eisawi D
Faculty of Medicine, University of Jordan, Amman.
J Ethnopharmacol. 1991 Mar;31(3):373-81. doi: 10.1016/0378-8741(91)90021-5.
The effects of an ethanol extract of Ferula sinaica roots on the smooth muscles of rabbit and guinea pig were tested in vitro using isolated segments of intestine, trachea and aorta. The extract inhibited the spontaneous movements of rabbit jejunum and guinea pig ileum and acetylcholine-induced contractions. The extract also inhibited the contractions of rabbit tracheal smooth muscle induced by acetylcholine stimulation and the contractions of guinea pig tracheal smooth muscle induced by histamine stimulation. Furthermore, the extract inhibited the contractions of rabbit aorta induced by norepinephrine stimulation. These inhibitions were concentration-dependent and reversible.
使用兔和豚鼠的离体肠段、气管段和主动脉段，在体外测试了阿魏（Ferula sinaica）根乙醇提取物对其平滑肌的作用。该提取物抑制兔空肠和豚鼠回肠的自发运动以及乙酰胆碱诱导的收缩。该提取物还抑制乙酰胆碱刺激诱导的兔气管平滑肌收缩以及组胺刺激诱导的豚鼠气管平滑肌收缩。此外，该提取物抑制去甲肾上腺素刺激诱导的兔主动脉收缩。这些抑制作用呈浓度依赖性且是可逆的。
