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白花蛇舌草:其肝脏保护活性的研究

Boerhaavia diffusa: a study of its hepatoprotective activity.

作者信息

Chandan B K, Sharma A K, Anand K K

机构信息

Department of Pharmacology, Council of Scientific and Industrial Research, Jammu Tawi, India.

出版信息

J Ethnopharmacol. 1991 Mar;31(3):299-307. doi: 10.1016/0378-8741(91)90015-6.

DOI:10.1016/0378-8741(91)90015-6
PMID:2056758
Abstract

An alcoholic extract of whole plant Boerhaavia diffusa given orally exhibited hepatoprotective activity against experimentally induced carbon tetrachloride hepatotoxicity in rats and mice. The extract also produced an increase in normal bile flow in rats suggesting a strong choleretic activity. The extract does not show any signs of toxicity up to an oral dose of 2 g/kg in mice.

摘要

口服地锦草全草的乙醇提取物对实验诱导的大鼠和小鼠四氯化碳肝毒性具有肝保护活性。该提取物还能使大鼠正常胆汁流量增加,表明其具有较强的利胆活性。在小鼠中,口服剂量达2 g/kg时,该提取物未表现出任何毒性迹象。

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