Division of Plastic and Reconstructive Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Semin Plast Surg. 2009 May;23(2):141-7. doi: 10.1055/s-0029-1214166.
The current management for chronic osteomyelitis centers on adequate antibiotic coverage and surgical debridement of nonviable tissue. The eradication of osteomyelitis, however, often involves a prolonged and frustrating course of management. Nonsurgical adjunctive modalities have not been widely used, mostly due to a lack of perceived efficacy, and have remained in a state of infancy. In this article, we will outline the rationale, current status, and evidence for several potential adjuncts to osteomyelitis management.
目前,慢性骨髓炎的治疗主要集中在充分的抗生素覆盖和对无活力组织的手术清创上。然而,骨髓炎的根除通常涉及一个漫长而令人沮丧的治疗过程。非手术辅助治疗方法尚未得到广泛应用,主要是因为其疗效不明显,并且仍处于起步阶段。在本文中,我们将概述几种潜在的骨髓炎治疗辅助方法的原理、现状和证据。