Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA.
J Autism Dev Disord. 2011 Mar;41(3):287-301. doi: 10.1007/s10803-010-1051-6.
We investigated whether deficits in social gaze and affect and in joint attention behaviors are evident within the first year of life among siblings of children with autism who go on to be diagnosed with autism or ASD (ASD) and siblings who are non-diagnosed (NoASD-sib) compared to low-risk controls. The ASD group did not differ from the other two groups at 6 months of age in the frequency of gaze, smiles, and vocalizations directed toward the caregiver, nor in their sensitivity to her withdrawal from interaction. However, by 12 months, infants in the ASD group exhibited lower rates of joint attention and requesting behaviors. In contrast, NoASD-sibs did not differ from comparison infants on any variables of interest at 6 and 12 months.
我们研究了在自闭症儿童的兄弟姐妹中，那些随后被诊断为自闭症或自闭症谱系障碍（ASD）的儿童（ASD 组）和未被诊断为自闭症的儿童（NoASD-sib 组），以及低风险对照组，在自闭症谱系障碍（ASD）儿童的第一年中，是否存在社会注视和情感以及共同注意行为的缺陷。在 6 个月大时，ASD 组在注视、微笑和向照顾者发出的声音的频率，以及对她退出互动的敏感性方面，与其他两组没有差异。然而，到 12 个月时，ASD 组的婴儿表现出较低的共同注意和请求行为的频率。相比之下，在 6 个月和 12 个月时，NoASD-sib 组在任何感兴趣的变量上都与对照组婴儿没有差异。
