School of Chemical Engineering Cornell University Ithaca, NY 14853.
Biotechnol Prog. 1986 Mar;2(1):53-60. doi: 10.1002/btpr.5420020110.
A multimembrane reactor is described. Four layers (gas, cells, nutrient, and solvent) are separated by membranes. This structure prevents solvent emulsification in the fermentation broth. The system was tested for ethyl alcohol production from glucose using yeast. Tributyl phosphate (TBP) was chosen as the extractant. Experiments demonstrate for the first time a successful extractive fermentation with a practical solvent. Prevention of emulsification removes the toxic effect of TBP on yeast metabolism.
介绍了一种多膜反应器。该反应器由四层（气体、细胞、营养物和溶剂）通过膜隔开。这种结构防止了溶剂在发酵液中的乳化。该系统采用酵母以葡萄糖为原料生产乙醇进行了测试。选择磷酸三丁酯（TBP）作为萃取剂。实验首次证明了使用实用溶剂进行成功的萃取发酵。乳化的防止消除了 TBP 对酵母代谢的毒性影响。
