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银屑病的局部治疗。

Topical treatment of psoriasis.

机构信息

The University of Manchester, Salford Royal Hospital (Hope), Manchester Academic Health Sciences Centre, Department of Dermatology, Salford, Manchester M6 8HD, UK.

出版信息

Expert Opin Pharmacother. 2010 Aug;11(12):1999-2009. doi: 10.1517/14656566.2010.492778.

Abstract

IMPORTANCE OF THE FIELD

The majority of patients with psoriasis can be safely and effectively treated with topical therapy alone, either under the supervision of a family physician or dermatologist. For those requiring systemic agents, topical therapies can provide additional benefit. Optimal use of topical therapy requires an awareness of the range and efficacy of all products.

AREAS COVERED IN THIS REVIEW

The review covers the efficacy and role of topical therapies including emollients, corticosteroids, vitamin D analogs, calcineurin inhibitors, dithranol, coal tar, retinoids, keratolyics and combination therapy. The report was prepared following a PubMed and Embase literature search up to April 2010.

WHAT THE READER WILL GAIN

The paper provides a broad review of the relevant topical therapeutic options available in routine clinical practice for the management of psoriasis and a recommendation for selection of treatment.

TAKE HOME MESSAGE

Topical therapies used appropriately provide a safe and effective option for the management of psoriasis. An awareness of the available products and their efficacy is key to treatment selection and patient satisfaction.

摘要

重要性的领域

大多数银屑病患者可以安全有效地治疗与局部治疗单独,无论是在监督下家庭医生或皮肤科医生。对于那些需要系统代理,局部治疗可以提供额外的好处。最佳的使用局部治疗需要意识到的范围和功效的所有产品。

涵盖领域在这审查

审查涵盖的疗效和作用的局部治疗包括保湿剂,皮质类固醇,维生素 D 类似物,钙调神经磷酸酶抑制剂,蒽林,煤焦油,类视黄醇,角质促成剂和联合治疗。报告编写后,PubMed 和 Embase 文献检索到 2010 年 4 月。

读者将获得

本文提供了一个广泛的审查有关的局部治疗方案可用于常规临床实践中治疗银屑病和推荐治疗选择。

带回家的消息

局部治疗的使用是安全有效的选择,管理银屑病。认识到现有的产品和疗效是治疗选择和病人满意度的关键。

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