Kurian A, Barankin B
Department of Medicine, McMaster University, Hamilton, ON, Canada 2.
Skin Therapy Lett. 2011 Jan;16(1):4-7.
Topical therapy forms the cornerstone of treatment in the management of psoriasis. It plays a significant role as monotherapy in mild to moderate psoriasis, and it is used predominantly as adjunctive therapy in moderate to severe forms of the disease. Over the past decade, the topical treatment of psoriasis has evolved from the age-old applications, such as coal tar, to the more cosmetically acceptable and efficacious options containing topical corticosteroids, vitamin D analogues, and combined agents. With the advent of topical therapies in tailored vehicles and sophisticated delivery modes, the outlook for effectively managing psoriasis with topical approaches appears promising. To ensure therapeutic success, patient education about the disease, treatment options, proper administration, and adverse effects is essential, which will alleviate the common problem of poor patient adherence and promote more optimal clinical outcomes.
局部治疗是银屑病管理中治疗的基石。在轻度至中度银屑病中，它作为单一疗法发挥着重要作用，而在中度至重度银屑病中，它主要用作辅助疗法。在过去十年中，银屑病的局部治疗已从古老的应用方法，如煤焦油，发展到更美观且有效的选择，包括局部用皮质类固醇、维生素D类似物和联合制剂。随着局部治疗在定制载体和复杂给药方式方面的出现，通过局部方法有效管理银屑病的前景似乎很乐观。为确保治疗成功，对患者进行有关疾病、治疗选择、正确给药和不良反应的教育至关重要，这将缓解患者依从性差这一常见问题，并促进更理想的临床结果。
