The National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, US Department of Health and Human Services, 10 Center Drive, Bethesda, MD 20892-1108, USA.
Addiction. 2011 Jun;106(6):1052-60. doi: 10.1111/j.1360-0443.2010.02995.x. Epub 2010 Jun 21.
The aim of this paper is to present a concise account of the history, mission, structure and some recent achievements of the US National Institute on Alcohol Abuse and Alcoholism (NIAAA). Created by the US Congress 40 years ago, the NIAAA has evolved from an entity charged mainly with building a national system of alcoholism treatment services to one with responsibility for developing, nurturing and supporting the biomedical and behavioral science foundation necessary to reduce the significant domestic and global public health impact of alcohol use disorders. The NIAAA is unique in that it functions both as a funding agency, supporting research at universities and other external, or 'extramural' research institutions, and is also a research institution itself, where alcohol research is carried out in-house, or 'intramurally'. Of a $450.2 million 2009 Congressional Appropriation, approximately 90% was devoted toward the former and approximately 10% towards the latter objective. The current NIAAA Strategic Plan builds on a new organizing principle for long-range research planning, based on a life-span perspective that recognizes that human biology and behavior continue to change throughout life and changes occurring throughout the life-span affect individuals' drinking patterns as well as the decisions they may make to change their drinking habits or to seek help for alcohol use problems. Within this framework, major efforts are currently being devoted to educating practitioners on clinically useful, science-based assessment and treatment methods that exist today, and development of personalized new treatments for tomorrow.
本文旨在简要介绍美国国家酒精滥用和酗酒研究所(NIAAA)的历史、使命、结构和近期成就。该研究所由美国国会于 40 年前创建,其职责已经从主要负责建立全国性的酗酒治疗服务体系,演变为负责为减少国内和全球因酗酒导致的重大公共卫生问题,提供必要的生物医学和行为科学基础。NIAAA 的独特之处在于,它既是一个资助机构,支持大学和其他外部(“院外”)研究机构的研究,也是一个内部(“院内”)进行酒精研究的研究机构。在 2009 年 4.502 亿美元的国会拨款中,约 90%用于前者,约 10%用于后者。目前的 NIAAA 战略计划建立在一个新的长期研究规划组织原则基础上,该原则基于一个生命周期的视角,即人类生物学和行为在整个生命周期中持续变化,而整个生命周期中的变化会影响个人的饮酒模式以及他们可能做出的改变饮酒习惯或寻求帮助解决酗酒问题的决定。在这一框架内,目前正在大力投入,对现有的基于科学、对临床有帮助的评估和治疗方法进行教育,并为未来开发个性化的新治疗方法。