Man'kovskaia I N, Seredenko M M
Patol Fiziol Eksp Ter. 1991 Jan-Feb(1):39-41.
Experiments were conducted on 112 adult male Wistar rats to study the effect of preliminary ionol administration on the activity of oxidation enzymes and ultrastructure of the hematoparenchymatous barrier (HPB) in the myocardium in acute and prolonged hypoxic hypoxia. It is shown that ionol was conducive to minimal damage of HPB ultrastructures in hypoxia and had a positive effect on oxidation metabolism of the myocardium: removed inhibition of isocitrate and malate dehydrogenase, activated the key enzymes of transport of reduction equivalents in the mitochondria.
对112只成年雄性Wistar大鼠进行实验，以研究预先给予维生素E对急性和慢性低氧性缺氧时心肌中氧化酶活性和血-实质屏障（HPB）超微结构的影响。结果表明，维生素E有助于在缺氧时使HPB超微结构损伤最小化，并对心肌的氧化代谢产生积极影响：消除异柠檬酸和苹果酸脱氢酶的抑制作用，激活线粒体中还原当量转运的关键酶。
