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[低氧性缺氧时心肌和血液中中性肽酶及氧化酶的活性]

[Activity of neutral peptide hydrolases and oxidative enzymes in the myocardium and blood during hypoxic hypoxia].

作者信息

Ivashkevich A A, Man'kovskaia I N, Kurdanova A S

出版信息

Ukr Biokhim Zh (1978). 1990 Jul-Aug;62(4):55-60.

PMID:2238155
Abstract

The citric cycle dehydrogenases and neutral peptide hydrolases (NPH) activity was determined in the myocardium and blood serum of Wistar rats under acute and prolonged hypoxic hypoxia. It was shown that the NPH activity and the activity of the most oxidative enzymes change in the same direction during adaptation to the high-altitude conditions. The role of the NPH in the oxidative metabolism reconstruction under acute and chronic hypoxia was discussed.

摘要

在急性和长期低氧性缺氧条件下,测定了Wistar大鼠心肌和血清中的柠檬酸循环脱氢酶及中性肽链内切酶(NPH)活性。结果表明,在适应高原环境过程中,NPH活性和大多数氧化酶的活性变化趋势相同。文中讨论了NPH在急性和慢性缺氧条件下氧化代谢重建中的作用。

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