Luan Lan, Wang Gang-li, Lin Rui-chao
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.
Zhong Yao Cai. 2010 Feb;33(2):220-1.
To study the chemical constituents of the extract with water from Forsythia suspensa.
The compounds were isolated and repeatedly purified on TLC, silica gel column chromatograph, gel column chromatography, and preparative HPLC, and the structures were elucidated by physico-chemical properties and NMR.
Eight compounds were obtained and elucidated as stearic acid(I), ursolic acid(II),p-hydroxyphenyl acetic acid(III),3-(4-ehtoxoy-3-hydroxyphenyl)acrylic acid(IV),isolariciresinol(V), epipinoresinol-4-O-beta-D-glucoside(VI),(+)-epipinoresionl(VII),(+)-pinoresinol(VIII).
Compound III is isolated from this genus for the first time.
研究连翘水提取物的化学成分。
通过薄层色谱、硅胶柱色谱、凝胶柱色谱和制备型高效液相色谱对化合物进行分离和反复纯化，并通过理化性质和核磁共振对结构进行鉴定。
得到8个化合物，分别鉴定为硬脂酸（I）、熊果酸（II）、对羟基苯乙酸（III）、3-（4-乙氧基-3-羟基苯基）丙烯酸（IV）、异落叶松脂素（V）、表松脂醇-4-O-β-D-葡萄糖苷（VI）、（+）-表松脂醇（VII）、（+）-松脂醇（VIII）。
化合物III首次从该属植物中分离得到。
