Kent Institute of Medicine and Health Sciences, University of Kent at Canterbury, Canterbury, Kent, UK.
Addict Biol. 2000 Apr 1;5(2):187-94. doi: 10.1080/13556210050003784.
Traditionally, researchers working in the field of genetics and alcoholism have used treatment centres and clinics to try and recruit suitable subjects for research purposes. The current study considered a diverse range of possible sources to recruit suitable families for a linkage study of alcoholism. These sources included the press, personal contacts and circular letters to alcohol treatment centres and members of the Substance Misuse Section of the Royal College of Psychiatrists. Only 9-14% of families contacted from any source were suitable for inclusion in the study, due to the strict selection criteria. Press contacts were found to be the most productive source of suitable families willing to participate in the study, accounting for over 50% of contacts and eventual subjects recruited. There appeared to be no bias in the affection status of subjects recruited from the different sources. For future genetic studies of alcoholism it might be worthwhile to utilize this source more fully. Reasons for exclusion from the study are also considered, with the most common reasons being non-co-operation and no family history.
传统上，从事遗传学和酗酒研究的研究人员曾利用治疗中心和诊所来尝试招募合适的研究对象。本研究考虑了多种可能的来源，以招募适合酗酒症连锁研究的合适家庭。这些来源包括媒体、个人联系以及给酒精治疗中心和皇家精神病学院物质滥用科成员的传阅信。由于严格的选择标准，只有 9-14%的联系家庭适合纳入研究。发现媒体联系是最有可能提供愿意参与研究的合适家庭的来源，占联系和最终招募对象的 50%以上。从不同来源招募的研究对象的情感状况似乎没有偏见。对于未来的酗酒症遗传学研究，充分利用这一来源可能是值得的。还考虑了被排除在研究之外的原因，最常见的原因是不合作和没有家族史。
