Seaton Kimberly L, Cornell Jodi L, Wilhelmsen Kirk C, Vieten Cassandra
Ernest Gallo Clinic and Research Center, University of California, San Francisco, USA.
Alcohol Clin Exp Res. 2004 Jan;28(1):78-84. doi: 10.1097/01.ALC.0000107200.88229.57.
Recruiting a large number of participants meeting strict inclusion criteria can be challenging, particularly when selecting for a condition associated with a social stigma such as alcoholism, when participation involves collection of medical specimens and sensitive information, and when the participation of family members or other collaterals is required. Developing and implementing a successful recruitment plan depends upon identifying the most effective recruitment strategies given the available resources.
Several strategies for recruiting subjects for a large family study on the genetics of alcoholism were evaluated over a two-year period with regard to participant yield, time and cost expenditure.
Overall effectiveness of a recruitment strategy was determined based on a composite of yield, cost and time expenditure. The most effective recruitment strategies were direct mail, press release, the Internet and treatment center collaborations.
Results provide insight into successful strategies for recruiting large numbers of participants and their family members selected for a condition associated with a social stigma.
招募大量符合严格纳入标准的参与者可能具有挑战性，特别是在选择与社会污名相关的疾病（如酗酒）时，当参与涉及医学标本和敏感信息的收集时，以及当需要家庭成员或其他旁系亲属参与时。制定和实施成功的招募计划取决于在现有资源的情况下确定最有效的招募策略。
在两年时间里，对几种为一项关于酗酒遗传学的大型家族研究招募受试者的策略进行了评估，评估内容包括参与者数量、时间和成本支出。
根据产量、成本和时间支出的综合情况确定招募策略的总体有效性。最有效的招募策略是直接邮寄、新闻稿、互联网和与治疗中心合作。
研究结果为招募大量符合与社会污名相关疾病条件的参与者及其家庭成员的成功策略提供了见解。
