Department of Oral and Maxillofacial Surgery, University of Erlangen-Nuremberg, Erlangen, Germany.
Int J Oral Maxillofac Surg. 2010 Sep;39(9):897-903. doi: 10.1016/j.ijom.2010.05.005. Epub 2010 Jun 23.
The osteoinductive potential of periosteum and bone can be stimulated by elevating the periosteum in a distraction-like modus, but also by an ad-hoc elevation. This was tested and proved in an experiment in 9 Goettingen mini-pigs with elevation heights of 5, 10 and 15mm. Specially designed and perforated titanium meshes were implanted subperiosteally to compare the dynamic elevation procedure with static shielding. The cumulative results for bone formation underneath the mesh were 66% in dynamic and 67% in non-dynamic elevation. The cumulative results for mineralization of the bone regenerates in comparison with the underlying basal bone of the skull showed independently from the technique applied no difference bigger than 5%. No major difference in bone formation could be observed in this pilot study. The main advantages of dynamic periosteal elevation and static shielding are minimal invasion and morbidity. Periosteal elevation could be applied in cranio-maxillofacial surgery, in preimplantological augmentation and in reconstructive surgery of the skull; applications in other specialties may be possible.
骨膜和骨的成骨潜力可以通过在类似于牵引的模式下抬高骨膜来刺激，也可以通过专门的抬高来刺激。这在一项针对 9 只哥廷根小型猪的实验中进行了测试和证明，实验中抬高高度分别为 5、10 和 15mm。专门设计和穿孔的钛网被植入骨膜下，以比较动态抬高和静态屏蔽的程序。在网下形成的骨的累积结果为动态 66%和非动态 67%。与颅骨基底骨相比，骨再生的矿化累积结果表明，无论应用何种技术，差异均不超过 5%。在这项初步研究中，未观察到骨形成的明显差异。动态骨膜抬高和静态屏蔽的主要优点是微创和低发病率。骨膜抬高可应用于颅面外科、植入前骨增量和颅骨重建手术；其他专业的应用也可能是可行的。
