Department of Cranio-Maxillofacial Surgery, Maastricht University Medical Center, Maastricht NL-6202AZ, The Netherlands.
J Biomed Mater Res B Appl Biomater. 2010 Oct;95(1):126-30. doi: 10.1002/jbm.b.31691.
Due to its osteoinductive potential, the periosteum plays a crucial role in the process of neoosteogenesis. Therefore, periosteal elevation can lead to new bone formation in an artificially created space. In this study, we compared dynamic periosteal elevation with static shielding in an animal experiment. Different elevation/shielding heights of 5, 10, and 15 mm were tested with regard to various consolidation periods. Histological analysis, histomorphometry, and microradiography were used to measure the quantity and quality of the newly formed bone. No significant differences regarding bone quantity or quality were found between the two techniques. The cumulative results for the bone regeneration in the space created by distraction/elevation were about 66% in the dynamic and 67% in static procedure. The main advantages of both techniques are minimal invasion and low morbidity. In terms of clinical applications, periosteal elevation could be applied in cranio-maxillofacial surgery, in pre-implant augmentation and in reconstructive surgery.
由于其成骨诱导潜力，骨膜在新骨生成过程中起着至关重要的作用。因此，骨膜提升可以在人为创造的空间中导致新骨形成。在这项动物实验研究中，我们比较了动态骨膜提升与静态屏蔽的效果。针对不同的愈合期，测试了 5、10 和 15 毫米的不同提升/屏蔽高度。组织学分析、组织形态计量学和微射线照相术用于测量新形成骨的数量和质量。两种技术在骨量或质量方面没有发现显著差异。通过牵张/提升在空间中创建的骨再生的累积结果在动态组中约为 66%，在静态组中约为 67%。这两种技术的主要优点是微创和低发病率。就临床应用而言，骨膜提升可应用于颅面外科、植入前骨增量和重建外科。
