Good D J, Dill S, Mossi S, Frey R, Beglinger C, Stalder G A, Meyer-Wyss B
Abteilung für Gastroenterologie, Kantonsspital Basel.
Schweiz Med Wochenschr. 1991 May 18;121(20):764-6.
A simplified 13C-urea breath test (UBT) for detection of Helicobacter pylori (Hp) infection was evaluated in 50 patients. Following upper gastrointestinal endoscopy the patients received 100 ml of a liquid test meal with 100 mg 13C-urea. Breath samples were obtained at baseline and 30 minutes respectively. The UBT was positive (difference of 13CO2 enrichment exceeding 5%) in 33/35 patients with culture-proven Hp infection and negative in 14/15 patients in whom microbiological culture, histology and a urease test (CLO-test) were negative. We conclude that in view of its high sensitivity (94%) and specificity (93%) the UBT is useful for rapid, non-invasive diagnosis of Hp infection.
对50例患者进行了用于检测幽门螺杆菌（Hp）感染的简化13C尿素呼气试验（UBT）评估。在进行上消化道内镜检查后，患者服用含100mg 13C尿素的100ml液体试验餐。分别在基线和30分钟时采集呼气样本。在35例经培养证实有Hp感染的患者中，33例UBT呈阳性（13CO2富集差异超过5%），在15例微生物培养、组织学检查和尿素酶试验（CLO试验）均为阴性的患者中，14例UBT呈阴性。我们得出结论，鉴于其高敏感性（94%）和特异性（93%），UBT可用于快速、无创诊断Hp感染。
