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腹腔镜右半结肠切除术入路的前瞻性随机对照试验:由内侧向外侧与由外侧向内侧对比

[A prospective randomized control trial of the approach for laparoscopic right hemi-colectomy:medial-to-lateral versus lateral-to-medial].

作者信息

Yan Jun, Ying Min-gang, Zhou Dong, Chen Xia, Chen Lu-chuan, Ye Wen-fei, Zang Wei-dong

机构信息

Department of Abdominal Surgery, Fujian Provincial Tumor Hospital, Fuzhou 350014, China.

出版信息

Zhonghua Wei Chang Wai Ke Za Zhi. 2010 Jun;13(6):403-5.

Abstract

OBJECTIVE

To compare the medial-to-lateral approach with the lateral-to-medial approach in laparoscopic right hemi-colectomy for right colon cancer.

METHODS

A prospective randomized controlled trial was performed in the Fujian provincial tumor hospital between January 2007 and July 2009. Forty-eight cases with right colon cancer were randomly divided into two groups:medial-to-lateral laparoscopic right hemi-colectomy group(group M) and lateral-to-medial laparoscopic right hemi-colectomy group(group L). Primary outcome(operative time) and secondary outcomes (estimated blood loss, intra-operative complication, post-operative complication, number of lymph node retrieval, hospital stay) were compared between two groups.

RESULTS

Operative time was(122.5+/-25.8) min in group M and (162.9+/-30.9) min in Group L (P=0.01). Estimated blood loss was(55.8+/-36.2) ml in group M and (104.6+/-58.2) ml in group L(P=0.01). There were no significant differences between the two groups in intra-operative complications(4.2% vs 8.3%, P=1.00), post-operative complications (8.3% vs 16.7%, P=0.66), number of lymph node retrieval (17.4+/-3.2 vs 17.8+/-3.4, P=0.67), and hospital stay[(7.8+/-2.2) d vs (8.0+/-3.6) d, P=0.81].

CONCLUSION

The medial-to-lateral approach reduces operative time and blood loss in laparoscopic right hemi-colectomy as compared with the lateral-to-medial approach.

摘要

目的

比较腹腔镜右半结肠切除术治疗右半结肠癌时由内侧向外侧入路与由外侧向内侧入路的效果。

方法

2007年1月至2009年7月在福建省肿瘤医院进行一项前瞻性随机对照试验。48例右半结肠癌患者被随机分为两组:由内侧向外侧腹腔镜右半结肠切除术组(M组)和由外侧向内侧腹腔镜右半结肠切除术组(L组)。比较两组的主要结局(手术时间)和次要结局(估计失血量、术中并发症、术后并发症、淋巴结清扫数量、住院时间)。

结果

M组手术时间为(122.5±25.8)分钟,L组为(162.9±30.9)分钟(P = 0.01)。M组估计失血量为(55.8±36.2)毫升,L组为(104.6±58.2)毫升(P = 0.01)。两组在术中并发症(4.2% 对8.3%,P = 1.00)、术后并发症(8.3% 对16.7%,P = 0.66)、淋巴结清扫数量(17.4±3.2对17.8±3.4,P = 0.67)和住院时间[(7.8±2.2)天对(8.0±3.6)天,P = 0.81]方面无显著差异。

结论

与由外侧向内侧入路相比,由内侧向外侧入路可减少腹腔镜右半结肠切除术的手术时间和失血量。

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