9-（2-羟乙氧甲基）鸟嘌呤对疱疹病毒组病毒的活性。
9-(2-hydroxyethoxymethyl) guanine activity against viruses of the herpes group.
作者信息
Schaeffer H J, Beauchamp L, de Miranda P, Elion G B, Bauer D J, Collins P
出版信息
Nature. 1978 Apr 13;272(5654):583-5. doi: 10.1038/272583a0.
DOI:10.1038/272583a0
PMID:205792
Abstract
Of a series of nucleoside analogues synthesised, 9-(2-hydroxyethoxymethyl) guanine was found to have marked antiviral activity in animal models of herpes virus infections, associated with very low toxicity.
摘要
在合成的一系列核苷类似物中，发现9-(2-羟乙氧甲基)鸟嘌呤在疱疹病毒感染的动物模型中具有显著的抗病毒活性，且毒性极低。
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