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[实验性牙周炎中牙槽突骨组织的物理化学研究]

[Physicochemical research on the bone tissue of the alveolar process in experimental periodontitis].

作者信息

Zazulevskaia L Ia, Kogan G V

出版信息

Stomatologiia (Mosk). 1991 Jan-Feb;70(1):9-12.

PMID:2057967
Abstract

The thermal behavior of inorganic and organic components of the osseous tissue of the mandible alveolar process from experimental animals was first examined in health, elementary periodontitis and during its magnetic laser therapy. The derivatograms of the diseased osseous tissue were characterized by shifted maximum of the thermal effects observed towards the high temperature region and new peaks at 390 and 500 degrees C, which showed that highly boiling polypeptide fractions resistant to oxidation were prevalent in the organic matrix of osseous tissue. The abnormal process in the osseous tissue was largely explained by the conformational rearrangement of protein molecules, which in turn causing changes in their functional properties associated with formation of insoluble inorganic phosphate of routine composition and structure. As a result of magnetic laser therapy, thermic transformations in the examined samples followed the scheme that was close to thermal analysis of intact osseous tissue.

摘要

首次对实验动物下颌牙槽突骨组织的无机和有机成分在健康状态、初期牙周炎及其磁激光治疗期间的热行为进行了研究。患病骨组织的衍生图谱的特征是,热效应的最大值向高温区域偏移,并且在390和500摄氏度出现新的峰值,这表明在骨组织的有机基质中普遍存在抗氧化的高沸点多肽组分。骨组织中的异常过程在很大程度上可以用蛋白质分子的构象重排来解释,而这反过来又会导致其功能特性发生变化,这些变化与常规组成和结构的不溶性无机磷酸盐的形成有关。磁激光治疗的结果是,被检查样本中的热转变遵循了与完整骨组织热分析相近的模式。

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