Colella Giuseppe, Cannavale Rosangela, Flamminio Federica, Foschini Maria P
Department of Head and Neck Pathology, Second University of Naples, Naples, Italy.
J Oral Maxillofac Surg. 2010 Sep;68(9):2146-53. doi: 10.1016/j.joms.2009.09.064. Epub 2010 Jul 1.
The aim of this study was to provide a systematic review of fine-needle aspiration (FNA) cytology on salivary gland lesions.
A review of the literature was carried out using PubMed, SCIRUS, and the Cochrane Central Register of Controlled Trials (CENTRAL). The present study included only data correlating cytological and histological diagnoses.
Of the patients, 484 received a histological diagnosis of malignant tumor; cytological diagnosis was concordant in 387 (79.95%), discordant in 97 (20.04%). A total of 1,275 patients received a histological diagnosis of benign tumor; cytological diagnosis was concordant in 1,219 (95.608%) and discordant in 56 (4.39%). In all, 154 patients received a histological diagnosis of non-neoplastic lesion; cytological diagnosis was concordant in 145 (94.156%) and discordant in 9 (5.84%).
FNA is a safe diagnostic tool that has a reliable sensitivity and specificity for the assessment of salivary gland pathology. FNA cytology may be useful in routine preoperative diagnostic testing.
本研究旨在对唾液腺病变的细针穿刺（FNA）细胞学检查进行系统评价。
使用PubMed、SCIRUS和Cochrane对照试验中央注册库（CENTRAL）对文献进行综述。本研究仅纳入了细胞学诊断与组织学诊断相关的数据。
在这些患者中，484例接受了恶性肿瘤的组织学诊断；细胞学诊断与之相符的有387例（79.95%），不相符的有97例（20.04%）。共有1275例患者接受了良性肿瘤的组织学诊断；细胞学诊断与之相符的有1219例（95.608%），不相符的有56例（4.39%）。总共有154例患者接受了非肿瘤性病变的组织学诊断；细胞学诊断与之相符的有145例（94.156%），不相符的有9例（5.84%）。
FNA是一种安全的诊断工具，对评估唾液腺病变具有可靠的敏感性和特异性。FNA细胞学检查在常规术前诊断检测中可能有用。
